My husband is in the process of being approved for a kidney/pancreas transplant and since marijuana is not legal in SC he is having to go through an addiction class and test clean to be approved. He has been a daily smoker for many years and I was wondering if this would help decrease any issues he may have when he quits. He has some depression and anxiety especially lately due to medical issues. He is a Type 1 diabetic with CKD and will probably be on dialysis within the next few months. He also has diabetic neuropathy, retinopathy, and hypothyroidism Will your product be ok for him to take and will it help him? He cannot take NSAIDs due to his kidney disease. Thanks

Guzmán is a biochemist who’s studied cannabis for about 20 years. I visit him in his office at the Complutense University of Madrid, in a golden, graffiti-splotched building on a tree-lined boulevard. A handsome guy in his early 50s with blue eyes and shaggy brown hair tinged with gray, he speaks rapidly in a soft voice that makes a listener lean forward. “When the headline of a newspaper screams, ‘Brain Cancer Is Beaten With Cannabis!’ it is not true,” he says. “There are many claims on the Internet, but they are very, very weak.”

Kent, My mother has suffered from severe migraines since she was a child. Six weeks ago, she received the hemp oil tincture (I do not know what dosage). She does not take it daily. She rubs a drop or two on her temples at the start of a migraine. The drops worked more effectively for her than her medication did, and now that is all she uses. Hope this helps.
Some individuals have been found to have mutations on the CNR1 gene, which is responsible for coding the CB1 receptor (a type of receptor in cells throughout your body that interacts with cannabinoids). Issues with the CNR1 gene can ultimately result in a poorly functioning endocannabinoid system, which is an important variable when figuring out how to use CBD oil.
Considering the complete non-addictiveness and safety of cannabis, Dr. James Hudson, PhD, Professor Emeritus, University of British Columbia Department of Pathology and Lab Medicine, has said that pharmaceutical companies have an enormous incentive to chemically recreate the natural compounds in marijuana and somehow sell a drug from it. You probably already know this, but pharmaceutical companies can’t patent a natural compound, but if they can make a synthetic compound that mimics ingredient from cannabis, they can formulate that as a drug and potentially make a lot more money off of it.
“THC”—the more-famous, high-inducing compound in cannabis—“works directly on the cannabinoid system, meaning it attaches to receptors and mimics some of our own internal endocannabinoids,” says Igor Grant, a professor and chair of psychiatry at the University of California, San Diego School of Medicine. But CBD’s interaction with the endocannabinoid system is subtler. “Normally, these endocannabinoid-signaling molecules are broken down by enzymes, and one thing CBD does is interfere with the actions of those enzymes.”
THC, an intoxicating and illegal substance, is responsible for causing marijuana users to get “high.” Unlike THC, CBD is non-psychoactive because it does not act on the same pathways as THC. Thus, it is impossible to get “high” by smoking or ingesting CBD or CBD oil extracted from industrial hemp plants, as they only have minuscule traces of THC (<0.3%).
I wanted to know something about your part in the absorption of CBD. You talked about how CBD is non water-soluble and the best way to get the full effect is to either take a large amount OR vaporize it which you considered to be annoying or unnecessary. I on the other hand have no quarrels with doing this as I am an occasional smoker. Since you didn’t elaborate much on vaporizing, does this imply that it is still an adequate route to getting a better effect of CBD?
Research conducted by Vandrey and his colleagues has even shown that some CBD products contain significant levels of THC—which could get a child high and cause other unpleasant side effects. “This is an area that exists in a grey area of legality,” Vandrey says. “And because of that, anyone thinking about using cannabidiol, of any type, should proceed with caution.”
I tried CBD oil and it was just as useful for pain as yoga. This expensive commodity is just another catch phrase replacement theology trying to be substituted for what used to be adequate pain control treatment. Today at least my Dr stands there and says sorry as he lowers the dose by another pill. Thank you for trying. Our last ditch effort on Earth will be no doubt be to smoke MJ..
CBD oil has been used traditionally for thousands of years to relieve pain and ease discomfort, but only recently has the medical community once more embraced its healing capabilities. Many people, including experts and researchers, have praised the incredible therapeutic potential of cannabinoids, especially when applied topically as an oil to ease joint pain. (1) (2)
I sustained a brain & spine injury 4.5 years ago. I’ve followed all therapies religiously & taken meds as instructed but have not responded as my dr’s & ot’s/pt’s would like. I still have 3 herniated discs in my neck, double vision, chronic headaches, and neck, upper back & shoulder pain. My neuro had me on 2 different muscle relaxants, an anti-convulsant, sleep aid, anti-depressant, and anti-anxiety medications, so I was also on meds to deal with the side effects of those meds. I was so sedated that 3mos ago I fell during the night and re-concussed. My neuro’s solution was to increase my sleep aid so I wouldn’t sleep walk. Instead I took back my health and began reducing my medications. I heard about cbd 6wks ago & haven’t looked back. I’m currently at 600mg, am off the sleep aid & 1 muscle relaxant entirely, have the other relaxant at 50% dose, and have begun lowering the anti-convulsant dose. I haven’t taken the anxiety med at all and will begin working on the anti-depressant with my other dr soon. I feel better and have more energy and less pain than I ever did when taking all those meds. I still have word lapses and my brain feels “off”, but overall I feel more present. A huge surprise side effect has been weight loss – I gained 70lbs the first 8mos of my injury through inactivity and courses of prednisone and STRUGGLED to lose it. Since taking cbd I’ve lost 15lbs with no other changes. I’ll continue to work on my dose as I reduce the remainder of my prescription meds. I still feel aching soreness even pain when I’ve increased activity levels, but I have a lot of damage to my cervical vertebrae so know I may need to increase my daily cbd dose or carry a quick delivery smaller dose with me to supplement what I normally take. Before my injuries I was an athlete training to qualify for the U.S. open/masters team. Since then, Ive lived with limited range of motion and have been told I’ll never be able to return to the activities I’ve done in the past and certainly will never do impact activities again. I’ve lost significant time with my family because of this. I now have my sights on activity again and am slowly doing more with my them. I’m realistic and will see where things go in terms of returning to impact activities, but just by controlling the pain to this degree, cbd is literally giving me back my life.
Cons: The CBD cartridges used in vape pens can contain a solvent called propylene glycol, which is also used in e-cigarettes containing nicotine, Earleywine says. At high temperatures, propylene glycol can degrade into formaldehyde, a chemical that can irritate the nose and eyes and could increase the risk of asthma and cancer. Earleywine suggests looking for CBD vape pens that advertise “solvent-free oils.”
Cannabinoids may offer significant “side benefits” beyond analgesia. These include anti-emetic effects, well established with THC, but additionally demonstrated for CBD (Pertwee 2005), the ability of THC and CBD to produce apoptosis in malignant cells and inhibit cancer-induced angiogenesis (Kogan 2005; Ligresti et al 2006), as well as the neuroprotective antioxidant properties of the two substances (Hampson et al 1998), and improvements in symptomatic insomnia (Russo et al 2007).
Adam: What I bought was a 1 oz bottle of PLUS Raw CBD Oil drops. Bottle says 1 mg CBD per dose (2 sprays). I have chronic back and neck pain due to arthritis. After 5 days of the spray, I have gotten no relief of the pain. (To be fair, no amount of Aleve, ibuprofen, or aspirin gives me any relief) I’m 66 years old and new at this, so any advice would help.
Many people commonly reach for over-the-counter pharmaceuticals to relieve pain and stiffness, but these can come with a wide array of side effects, including damage to the liver, kidneys, and stomach lining. (3) For those who prefer a more gentle, natural approach to managing their joint pain and inflammation, CBD oil may provide relief without the long-term side effects found in many other pain relievers. (4)
Stage III Vulvar Cancer is visiting my body. I am taking CBD oil from the dispensary in Massachusetts. I put a rice grain size rubbed inside my mouth under my tongue. It is so terrible tasting, especially now with Chemo and Radiation, my stomach is ok, but I am getting almost nausea when putting the CBD Oil on my gums. Can I take it rectally or vaginally? Have you ever heard of this? Is it still just as effective as taken orally. I am only doing this because of my condition. It does help me sleep and I am more relaxed. I just wish I did not have to taste or smell it.
There is a tremendous difference between CBD from hemp vs the actual cannabis plant; not addressed the fact that you are discussing CBD from hemp in the beginning of the article is confusing to those who have not been able to do their own research yet. I’ve been trying different CBD products for 2 years now & at first read, I thought you were talking about cannabis.

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